คลังวารสาร

คลังวารสาร

แสดง 51 - 58 จาก 58 รายการ

Efficacy and Safety of Multiple Needle Revisions and 5-FU Injections in Over 14-month old Dysfunctional Blebs in Thai Patients

Created 2009-11-23 03:49:31 by คุณ System Administrator 311 Views

Objective: To evaluate efficacy and safety of multiple needle revisions and 5-FU injections in over 14-month old dysfunctional blebs in Thai patients. Methods: Eight eyes of 8 Thai patients who had surgically restored bleb function by using needle revision and 5-FU injection from one ophthalmologist, same technique in over 14-month old dysfunctional blebs in between January 2008 and April 2009 were enrolled, a retrospective study. The dysfunctional bleb was defined if the IOP less than 21 mmHg with anti-glaucoma medication or more than 21 mmHg with or without anti-glaucoma medication. The success of the needling revision was defined as absolute if the intraocular pressure (IOP) was < 21 mmHg without antiglaucoma medications. Bleb function was evaluated by slit-lamp biomicroscopic examination. Intraocular pressure measurement by applanation tonometry, morphology and degree of filtering bleb vascularization were evaluated and recorded. Intervention, either or both 5-FU or needling was performed when unsuccessful functioning bleb has been revealed to achieve target IOP less than 21 mmHg without antiglaucoma drugs. Results: Mean of needle revision times and 5- FU injections are 1.25 and 6.25 mg, respectively. There were 100% (8 cases) successes to achieve IOP less than 21 mmHg without anti-glaucoma medication for at least 3 months post-interventional. There was no report of serious complication or infection during and post-intervention. Conclusions: Needle revisions and 5-FU injections in over 14-month old dysfunctional blebs are simple, convenient, safe and effective in Thai patient.
Original Articles


Ocular Hypertension

Created 2009-11-23 03:53:48 by คุณ System Administrator 361 Views


Review Article







The Use of the Non-Mydriatic Fundus Camera in Glaucoma Evaluation

Created 2009-11-23 03:42:29 by คุณ System Administrator 429 Views

Objective: To evaluate the use of the non-mydriatic fundus camera in evaluation of optic nerve head vertical cup to disc ratio in glaucoma patients. Design: Cross-sectional descriptive comparative study Material and Method: Indirect ophthalmoscopy with 78 diopter lens and a digital non-mydriatic fundus camera were performed in forty two subjects (23 normal controls and 19 glaucoma). The estimated vertical cup to disc ratio (VCDR) from both methods were analyzed. The effect of the pupillary dilation on the estimation of VCDR from non-mydriatic fundus camera was also determined. Result: The mean ophthalmoscopically estimated VCDR was (mean ? SD) 0.479 ? 0.18, compared with a VCDR of (mean ? SD) 0.462 ? 0.18, measured with the non-mydriatic fundus camera (difference 0.017; 95% confidence interval [CI], 0.005-0.028; p=0.007). The overall correlation between the non-mydriatic fundus camera and indirect ophthalmoscopy with 78 D lens is 0.895 (p<0.001). From the receiver operating curve (ROC) at 90% specificity, the estimated VCDR from the non-mydriatic fundus camera yielded 68.4% sensitivity. Conclusion: The non-mydriatic fundus camera provided good correlation with minimal difference in the estimated VCDR, when compared with the standard indirect ophthalmoscopy with a 78 D lens. In conjunction with IOP measurement, a non-mydriatic fundus camera can make a useful tool for glaucoma screening.
Original Articles