เผยแพร่ผลงานวิจัยของจักษุแพทย์ไทย ในจดหมายข่าว Academy Express

Updated 2021-10-05 12:05:00

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เผยแพร่ผลงานวิจัยของจักษุแพทย์ไทย ในจดหมายข่าว Academy Express

September 2021

Academy Express ฉบับวันที่ 18 Sep 2021
Keratometric stability needed for 3 months after pterygium excision before additional procedures

Clinical stability of keratometric parameters after pterygium surgery is essential in patients requiring consecutive procedures, such as cataract surgery. This prospective observational study enrolled 75 eyes from 75 patients undergoing pterygium excision. Patients were evaluated monthly for 6 months. Forty percent and 73.3% of eyes, respectively demonstrated corneal astigmatic and corneal kerarometric stability at six months post-operation, while after 3 months of initial stability, 46.7% and 27.3% respectively. It is recommended that stability be achieved for at least three months before commencing with any additional procedures. Clinical Ophthalmology, March 2021.

https://pubmed.ncbi.nlm.nih.gov/33790535/

Academy Express ฉบับวันที่ 11 Sep 2021
Factors in visual outcome of open-globe injury repair by trainees

The authors studied the visual outcomes of trainees in primary repair of open-globe injury (OGI) and associated factors of the results. Most of the 78 cases over a 10-year period were managed well by the trainees, with little assistance needed from subspecialists. Poor initial visual acuity was associated with high risk of visual loss while higher ocular trauma scores were inversely related to lower risk of evisceration/enucleation. Clinical Ophthalmology, March 2021.

https://pubmed.ncbi.nlm.nih.gov/33790529/

 

Academy Express ฉบับวันที่ 4 Sep 2021
Accuracy of CT and MRI for patients with retinoblastoma

The authors assessed the diagnostic accuracy of magnetic resonance imaging and computed tomography for detecting the extent of tumor invasion in eyes with advanced retinoblastoma prior to enucleation. They concluded that CT showed poor diagnostic accuracy for four high-risk factors: scleral, choroidal, and anterior eye segment invasion, and post-laminar optic nerve invasion; and that MRI was moderately accurate for the latter. Current Eye Research, March 2021.

https://pubmed.ncbi.nlm.nih.gov/33752572/

 

August 2021

Academy Express ฉบับวันที่ 28 Aug 2021
Laser trabeculoplasty for glaucoma significantly reduces IOP

The researchers evaluated the efficacy and predictive factors of success after selective laser trabeculoplasty (SLT) for treating various types of open-angle glaucoma. Results showed that IOP and glaucoma medication usage significantly decreased after SLT. Treatment success was tied to more than 10% elevation in IOP at 1 hour whereas systemic hypertension and baseline IOP were negative predictors of SLT success. Clinical Ophthalmology, March 2021.

https://pubmed.ncbi.nlm.nih.gov/33776415/

 

Academy Express ฉบับวันที่ 14 Aug 2021
HPV infection is not tied to pterygium development

This study assessed the role of human papillomavirus (HPV) in pterygium pathogenesis. Analysis of 116 study patients did not reveal transmission of HPV through autoinoculation from the genital tract. Scientific Reports, February 2021.

https://pubmed.ncbi.nlm.nih.gov/33531557/

 

Academy Express ฉบับวันที่ 7 Aug 2021
Penetrating keratoplasty yields satisfactory outcomes in patients with Harboyan Syndrome

In this study, researchers describe 8 patients from 7 families with Harboyan Syndrome. All patients with bilateral cloudy corneas at birth and 11 eyes underwent penetrating keratoplasty. The overall corneal graft survival rate was 73% and the average graft survival time was 95 months. Outcomes after the procedure were satisfactory and were not tied to mutations in SLC4A11, the authors conclude. Journal of Human Genetics, February 2021.

https://pubmed.ncbi.nlm.nih.gov/32884076/

 

July 2021

Academy Express ฉบับวันที่ 31 Jul 2021
Study describes alleles associated with VKH

The study describes the frequency and association of gene alleles potentially associated with Vogt-Koyanagi-Harada (VKH) in patients from Northern Thailand. The findings suggest HLA-DRB1 and HLA-DQB1 may be potential markers for this disease. Ocular Immunology and Inflammation, February 2021.

https://pubmed.ncbi.nlm.nih.gov/32965138/

 

Academy Express ฉบับวันที่ 24 Jul 2021
Study reveals utility of portable visual acuity tests

In this study, investigators validated use of the Rosenbaum near vision card and a smartphone-based visual acuity test in 295 eyes. Both methods yielded visual acuity measurements that were comparable to standard ETDRS. These portable visual acuity tests may be useful during the COVID-19 pandemic, the authors conclude. Clinical Ophthalmology, February 2021.

https://pubmed.ncbi.nlm.nih.gov/33664563/

 

Academy Express ฉบับวันที่ 17 Jul 2021
Novel retinoblastoma therapy shows promise

This is the first study to describe a novel GD2-specific chimeric antigen receptor-modified T cell therapy against retinoblastoma. In vitro experiments demonstrate the therapy’s potential and suggest that it may improve when combined with immune checkpoint therapy. Translational Oncology, February 2021.

https://pubmed.ncbi.nlm.nih.gov/33321428/

 

Academy Express ฉบับวันที่ 10 Jul 2021
PPV with ILM peeling yields low closure rates for large full-thickness macular holes

Investigator evaluated the outcomes of pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling in 158 eyes with large idiopathic full-thickness macular holes (FTMH). They observed that closure rate was relatively low in these eyes. Surgical success was tied to a basal linear diameter of 1200 µm or smaller, no preoperative vitreomacular interface abnormality, extended ILM peeling and postoperative ellipsoid defect of 500 µm or smaller. Clinical Ophthalmology, February 2021.

https://pubmed.ncbi.nlm.nih.gov/33603330/

 

Academy Express ฉบับวันที่ 3 Jul 2021
Conjunctival intraepithelial neoplasia can manifest as a pigmented tumor

Investigators report a case of conjunctival intraepithelial neoplasia (CIN) in a patient with pigmented conjunctival lesion. Biomicroscopic examination revealed a gelatinous pigmented conjunctival mass with feeder vessels and conjunctival impression cytology confirmed it as CIN. The tumor responded well to treatment with 0.02% mitomycin C. Case Reports in Ophthalmology, January 2021.

https://pubmed.ncbi.nlm.nih.gov/33613255/