Mixture of 2.5% Phenylephrine
and 0.75% Tropicamide for Pupil Dilatation
Adisak Trinavarat M.D.
Auengporn Pituksung B.Sc.
Suthipol Udompunturak M.Sc.s
ABSTRACT Objective : To evaluate an efficacy and adverse effects of the eyedrop made from
10% phenylephrine and 1% tropicamide in the ratio of 1:3 for pupil dilatation.
Methods : The mixture
was instilled every 15 minutes, no more than 4 times to get the pupils dilated
to 8 mm in diameter. The study was conducted in 76 eyes of 39 patients with
the pupil diameters of 2.18 ± 0.56 (1-3) mm.
Results : Fifty-nine
eyes (77.6%) were dilated to 8 mm by 2.8 ± 0.7 (2-4) instillations.
In the remaining eyes, pupil diameters were 6.56 ± 0.73 (5-7) mm after
4 times of application. The pupils were dilated to 7 mm in 70 eyes (92.1%).
No significant changes in blood pressure and pulse rate were found in all
patients.
Conclusions : Mixture
of 2.5% phenylephrine and 0.75% tropicamide can be used effectively and
safely as a mydriatic drug.
Thai
J ophthalmol 1999 ; January-June 13(1) : 11-15.
Key word : Pupil
dilatation (mydriasis) phenylephrine mydriatices.-
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