Aminoglycoside-lnduced Retinal Toxicity

Sopa Wattananikorn M.D.
Somsanguan Ausayakhun M.D.
Winai Chaidaroon M.D.
Direk Patikulsila M.D.
Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200.

ABSTRACT : Intraocular aminoglycoside maybe cause in severe visual loss secondary to retinal toxicity, aminoglycoside-induced retinal toxicity (AIRT). We report a case of macular toxicity that occurred in a patient after three-time repetitive intraocular injections of amikacin, one into the anterior chamber and two into the vitreous cavity, within 4-day period for management of acute postoperative endophthalmitis following cataract surgery.

Key words : postoperative endophthalmitis, intraocular aminoglycoside, retinal toxicity