Intravitreal Ganciclovir for Cytomegalovirus Retinitis

Jutalal Tanterdtam, M.D.*
La-ongari Atchaneeyasakul, M.D.*
Surapol Suwannagool, M.D.**
* Department of Ophthalmology,
** Department of Preventive Medicine and Social, Faculty of Medicine Siriraj Hospital, Mahidol University

ABSTRACT The efficacy and tolerance of intravitreal ganciclovir for cytomegalovinis retinitis in patients with AIDS was studied.

Ganciclovir in a dose of 4 mig, 0.05 ml was injected into the vitreous of six patients who were treated at Siriraj Hospital during July to December 1994. They received the injection once a week. The main indication for intravitreal therapy was economic problem. The patients were followed for a mean period of 9 weeks (range 2-26 weeks) and total injections were 42. Lesions were improved 5-6 weeks after injection.

The complication were subconjunctival hemorrhages and central retinal artery occlusion.

Thai J Ophthalmol 1995 ; January-June 9(1): 11-18.